Portland Golf Club, established in 1914, is regarded as one of the most prestigious and challenging clubs in the Pacific Northwest. The club's location was chosen due to its proximity to the Spokane, Portland and Seattle railroad lines, and its course was designed by the club’s founding members. In 1946, Ben Hogan won the first of his nine major championships at Portland when it hosted the PGA Championship. In 1947, following a decade-long hiatus,  the USA Team won the 7th Ryder Cup over Great Britain and Ireland led by playing captain Hogan, Byron Nelson and Jimmy Demaret. In 1964, Portland underwent a significant redesign by Robert Trent Jones Sr., who is attributed as the course designer. Through decades of championship tradition, Portland’s tree-lined fairways and challenging green complexes have defined the club’s character. Miller Barber won the 1982 U.S. Senior Open at Portland Golf Club, Bill Ploeger won the 1999 U.S. Senior Amateur, and Hannah O’Sullivan won the 2015 U.S. Women’s Amateur at the historic venue. Among the legendary champions who have competed at Portland are Jack Nicklaus, Arnold Palmer and Bob Jones.

Originally designed by Herbert H. Barker in 1911, and updated by Walter Travis eight years later, Columbia Country Club remains remarkably similar to the original design. Columbia C.C. is known for its hilly and narrow setup, with challenging greens and a signature 18th hole that provides a spectacular view of the clubhouse. The prestigious club’s membership has included U.S. presidents and five-star generals. It previously hosted the 2021 U.S. Girls' Junior won by Rose Zhang, who had captured the U.S. Women's Amateur a year earlier at nearby Woodmont Country Club. The club will host the 2035 U.S. Senior Amateur eight years after the U.S. Senior Women's Amateur. 

Belle Meade Country Club, which was founded as Nashville Golf and Country Club in 1901, was originally located in the Whitworth area on West End Ave. At the annual meeting in 1911, club president Frank O. Watts recommended relocation to Belle Meade, an initiative that was carried out in 1916. Herbert H. Barker was responsible for the original golf course design, though ultimately Donald Ross completed the golf course, with contributions and updates to the course layout coming from Robert Trent Jones Sr. in the 1950s. In 2003, the golf course was again renovated under the supervision of golf architect Rees Jones and his associate Bryce Swanson. The inaugural U.S. Senior Amateur was hosted by Belle Meade in 1955 with J. Wood Platt taking the title. The 2028 U.S. Senior Women's Amateur will be the first USGA championship held at the venue since that '55 Senior Am. 

Historic Charles River Country Club, in Newton, Mass., will host a USGA championship for a second time, following the 2003 USGA Men's State Team Championship that was claimed by Tennessee. Charles River served as the stroke-play co-host for the 2013 U.S. Amateur that was contested at The Country Club, in Brookline. The Donald Ross design dates to 1921. Francis Ouimet, who stunned the golf world with his playoff triumph over English stalwarts Harry Vardon and Ted Ray in the 1913 U.S. Open at The Country Club, played out of Charles River for a number of years, and he served as an honorary member until his death in 1967. More recently, Ron Pritchard did an extensive renovation of the course.